CAS编号:21462-39-5 | 其他名称: 盐酸克林霉素 | MF:C18H33ClN2O5S.HCl |
产地:中国河南(大陆) | 类型:抗生素和抗菌剂 | 等级标准:医药级 |
品牌名称:MCT | Model USP/EP | 纯度:800ug/mg |
颜色:白色 | Form: Crystaler |
包装说明: | 25kg /桶 |
交货详细信息: | 提示 |
盐酸克林霉素 1.效力:800ug/mg min 2.标准:USP/EP 3.包装:25公斤/桶 4.GMP/ISO
项目 | SPEC。 | 成果 |
特征: | A WHITE OR ALMOST WHITE, CRYSTALER | 符合 |
鉴定 | 红外线吸收 | 符合 |
结晶度 | 符合要求 | 符合 |
酸度 | 100MG/ML SOLUTION: .0∼5.5 | 4.0 |
水 | 3.0~6.0% | 4.1% |
相关化合物 | 7-表林霉素 ≤ 4.0% | 1.0% |
| 克林霉素B≤2.0% | 0.5% |
| 其他个别相关物质≤1.0% | 0.3% |
| 所有相关物质总计≤6.0% | 2.6% |
化验 | ≥800μG/MG | 858μG/MG |
介绍:
克林霉素盐酸盐是克林霉素的水合盐酸盐。克林霉素是一种半合成抗生素,由母体化合物林可霉素的 7(R)-羟基进行 7(S)-氯取代而产生。
Clindamycin is indicated in the treatment of serious infections caused by susceptible anaerobic bacteria. Clindamycin is also indicated in the treatment of serious infections due to susceptible strains of streptococci, pneumococci, and stalococci. Its use should be reserved for penicillin-allergic patients or other patients for whom, in the judgment of the sician, a penicillin is inappropriate. Because of the risk of colitis, as described in the WARNING box, before selecting clindamycin the sician should consider the nature of the infection and the suitability of less tives (eg, erythromycin).
厌氧菌: Serious respiratory tract infections such as empyema, anaerobic pneumonitis and lung abscess; serious skin and soft tissue infections; septicemia; intra-abdominal infections such as peritonitis and intra-abdominal abscess (typically resulting from anaerobic organisms resident in the normal gastrointestinal tract); infections of the female pelvis and genital tract such as endometritis, nongonococcal tuboovarian abscess, pelvic litis and postsurgical vaginal cuff infection.
链球菌: 严重呼吸道感染;严重的皮肤和软组织感染。
链球菌: 严重呼吸道感染;严重的皮肤和软组织感染。
肺炎球菌: 严重呼吸道感染。
应进行细菌学研究以确定致病微生物及其对克林霉素的敏感性。
为了减少耐药细菌的产生并保持克林霉素和其他抗菌药物的有效性,盐酸克林霉素只能用于治疗或预防已证实或强烈怀疑由敏感细菌引起的感染。当获得培养和药敏信息时,在选择或修改抗菌治疗时应考虑这些信息。在缺乏此类数据的情况下,当地流行病学和易感性模式可能有助于经验性治疗选择。